ITGA4 antibody

Catalog No. ABIN135383

The Rat Monoclonal anti-ITGA4 antibody is suitable to detect ITGA4 in samples from Mouse. It has been validated for FACS, IP, IHC (fro) and BR.

Quick Overview for ITGA4 antibody (ABIN135383)

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This ITGA4 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR)

Clone: DATK32

Product Details anti-ITGA4 Antibody

Purpose: Rat Anti-Mouse LPAM-1-LE/AF

Specificity: Mouse LPAM-1

Characteristics: Low Endotoxin/Azide Free Anti-Mouse LPAM-1 antibody for use in flow cytometry, immunohistochemistry, immunoprecipitation, and blocking assays.

Endotoxin Level: Low Endotoxin

Immunogen: AKR/Cum mouse T lymphoma cell line TK-1

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Preservative: Azide free

Handling Advice: Each reagent is stable for the period shown on the bottle label if stored as directed.

Storage: 4 °C

Storage Comment: 2-8°C

Target Details for ITGA4

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Background: The lymphocyte Peyer's patch adhesion molecule (LPAM-1), also known as integrin 47, is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The 47 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM-1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria.

Gene ID: 16401

UniProt: Q00651

Pathways: Integrin Complex