LAMP1 antibody

Catalog No. ABIN135831

Cited in 4+ publications. The Mouse Monoclonal anti-LAMP1 antibody (Clone H4A3) (ABIN135831) specifically detects LAMP1 in WB, FACS, IP, ICC, IHC (p), IHC (fro), IEM and Purif. The antibody is reactive with Human, Green Monkey, Macaca (Macaque), Rhesus Monkey and Sooty mangabey (Cercocebus atys) samples.

Quick Overview for LAMP1 antibody (ABIN135831)

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Reactivity: Human, Green Monkey, Macaca (Macaque), Rhesus Monkey, Sooty mangabey (Cercocebus atys)

Host: Mouse

Clonality: Monoclonal

Conjugate: This LAMP1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoelectron Microscopy (IEM), Purification (Purif)

Clone: H4A3

Product Details anti-LAMP1 Antibody

Purpose: Mouse Anti-Human CD107a-UNLB

Specificity: Human/Rhesus/African Green Monkey/Pigtail Macaque/Sooty Mangabey CD107a, Mr 100-120 kDa

Characteristics: Purified Anti-Human CD107a antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, electron microscopy, western blotting, immunoprecipitation, and purification assays.

Immunogen: Human adherent peripheral blood cells

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: Borate buffered saline, pH 8.2

Storage: 4 °C

Storage Comment: 2-8°C

References for anti-LAMP1 antibody (ABIN135831)

Eriksson, Wäster, Öllinger: "Restoration of lysosomal function after damage is accompanied by recycling of lysosomal membrane proteins." in: Cell death & disease, Vol. 11, Issue 5, pp. 370, (2020) (PubMed).

Remacle, Hullugundi, Dolkas, Angert, Cieplak, Scott, Chernov, Shubayev, Strongin: "Interaction of the cryptic fragment of myelin basic protein with mitochondrial voltage-dependent anion-selective channel-1 affects cell energy metabolism." in: The Biochemical journal, Vol. 475, Issue 14, pp. 2355-2376, (2019) (PubMed).

Boman, Svensson, Boxer, Rojas, Seeley, Karydas, Miller, Kågedal, Svenningsson: "Distinct Lysosomal Network Protein Profiles in Parkinsonian Syndrome Cerebrospinal Fluid." in: Journal of Parkinson's disease, Vol. 6, Issue 2, pp. 307-15, (2016) (PubMed).

Armstrong, Mattsson, Appelqvist, Janefjord, Sandin, Agholme, Olsson, Svensson, Blennow, Zetterberg, Kågedal: "Lysosomal network proteins as potential novel CSF biomarkers for Alzheimer's disease." in: Neuromolecular medicine, Vol. 16, Issue 1, pp. 150-60, (2014) (PubMed).

Target Details for LAMP1

Target: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Alternative Name: CD107a

Background:

Description: Mouse Anti-Human CD107a-UNLB

NCBI_Official_Symbol: LAMP1, LAMP1, LAMP1, LAMP1, LAMP1

Synoynms: LAMP-1, lysosome-associated membrane protein 1

Gene ID: 3916, 697331, 103214841

UniProt: P11279

Pathways: Autophagy