RFTN2 antibody (AA 1-100)

Catalog No. ABIN1385314

This Rabbit Polyclonal antibody specifically detects RFTN2 in ELISA, WB, IF (cc), IF (p), IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for RFTN2 antibody (AA 1-100) (ABIN1385314)

Target: RFTN2 (Raftlin Family Member 2 (RFTN2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RFTN2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-RFTN2 Antibody

Binding Specificity: AA 1-100

Predicted Reactivity: Human,Mouse,Rat,Dog,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RFTN2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for RFTN2

Target: RFTN2 (Raftlin Family Member 2 (RFTN2))

Alternative Name: RFTN2

Background:

Synonyms: Raft-linking protein 2, Raftlin-2, Rftn2, RFTN2_HUMAN.

Background: Membrane microdomains known as lipid rafts are implicated in B-cell activation during B-cell receptor (BCR) signal initiation. Raftlin-2, also designated RFTN2 (raftlin family member 2) or raft-linking protein 2, is a 501 amino acid cell membrane protein that is essential for raft cell assembly and maintenance. A lipid anchor protein, Raftlin-2 belongs to the raftlin family and is encoded by a gene that maps to human chromosome 2q33.1 and mouse chromosome 1 C1.2. Human chromosome 2 is the second largest human chromosome, which consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome is due to mutations in the ALMS1 gene.

Gene ID: 130132