CRHBP antibody

Catalog No. ABIN1385519

The Rabbit Polyclonal anti-CRHBP antibody is suitable to detect CRHBP in samples from Human, Rat and Mouse. It has been validated for WB.

Quick Overview for CRHBP antibody (ABIN1385519)

Target: CRHBP (Corticotropin Releasing Hormone Binding Protein (CRHBP))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRHBP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CRHBP Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CRHBP

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CRHBP

Target: CRHBP (Corticotropin Releasing Hormone Binding Protein (CRHBP))

Alternative Name: CRHBP

Background:

Synonyms: CRH-BP, Corticotropin releasing hormone binding protein, CRF binding protein, CRF BP, CRH BP, Corticotropin releasing factor binding protein, CRFBP,

Background: CRHBP is a potent stimulator of synthesis and secretion of preopiomelanocortin derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH binding protein which inactivates CRH and which may prevent inappropriate pituitary adrenal stimulation in pregnancy.

Gene ID: 1393

Pathways: Negative Regulation of Hormone Secretion