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CADPS antibody (AA 151-250)

CADPS Reactivity: Human IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1385753
  • Target See all CADPS Antibodies
    CADPS (Ca++-Dependent Secretion Activator (CADPS))
    Binding Specificity
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-250
    Reactivity
    • 13
    • 8
    • 8
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 13
    • 1
    Rabbit
    Clonality
    • 14
    Polyclonal
    Conjugate
    • 12
    • 1
    • 1
    This CADPS antibody is un-conjugated
    Application
    • 11
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Immunohistochemistry (Frozen Sections) (IHC (fro))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CAPS1
    Isotype
    IgG
    Top Product
    Discover our top product CADPS Primary Antibody
  • Application Notes
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    CADPS (Ca++-Dependent Secretion Activator (CADPS))
    Alternative Name
    CAPS1 (CADPS Products)
    Synonyms
    CADPS1 antibody, CAPS antibody, CAPS1 antibody, Caps antibody, Caps1 antibody, Caps2 antibody, AU067781 antibody, mKIAA1121 antibody, CADPS antibody, cadps antibody, MGC122552 antibody, CAPS-1 antibody, caps antibody, caps1 antibody, si:busm1-1i3.1 antibody, si:busm1-6a2.7 antibody, si:dz6a2.7 antibody, calcium dependent secretion activator antibody, Ca2+-dependent secretion activator antibody, Ca2+-dependent activator protein for secretion b antibody, Ca2+ dependent secretion activator antibody, Ca2+ dependent secretion activator L homeolog antibody, Ca2+-dependent activator protein for secretion a antibody, CADPS antibody, Cadps antibody, cadpsb antibody, cadps antibody, cadps.L antibody, cadpsa antibody
    Background

    Synonyms: Cadps, CADPS1, Calcium dependent secretion activator 1, Calcium-dependent activator protein for secretion 1, Calcium-dependent secretion activator 1, Caps, CAPS-1, rCAPS, CAPS1_HUMAN.

    Background: Calcium-dependent secretion activators (CAPS-1 and CAPS-2) are calcium-binding proteins that direct neurotransmitter and neuropeptide-filled vesicles to the cell membrane for secretory granule exocytosis. Both CAPS-1 and CAPS-2 are expressed primarily in the brain where they regulate the secretion of various substances. The CAPS proteins contain a PH domain that is essential for regulation of exocytosis, as well as regulation of phospholipid binding. Through their regulation of neurotrophin release from granule cells, CAPS proteins help to regulate cell fate during neuronal development. CAPS-1 is thought to regulate catecholamine release from neuronal cells, while CAPS-2 is thought to regulate release of both brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3) from granule cells. Defects in the genes encoding CAPS-1 and CAPS-2 are implicated in impaired cerebral development and autism.

    Pathways
    Synaptic Vesicle Exocytosis
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