PTPRR antibody (AA 165-270)
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- Target See all PTPRR Antibodies
- PTPRR (Protein tyrosine Phosphatase, Receptor Type, R (PTPRR))
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Binding Specificity
- AA 165-270
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PTPRR antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
- Predicted Reactivity
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human PCPTP1
- Isotype
- IgG
- Top Product
- Discover our top product PTPRR Primary Antibody
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- Application Notes
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- PTPRR (Protein tyrosine Phosphatase, Receptor Type, R (PTPRR))
- Alternative Name
- PCPTP1 (PTPRR Products)
- Synonyms
- EC-PTP antibody, PCPTP1 antibody, PTP-SL antibody, PTPBR7 antibody, PTPRQ antibody, Pcptp1 antibody, ec-ptp antibody, pcptp1 antibody, ptp-sl antibody, ptpbr7 antibody, PTPRR antibody, Gmcp1 antibody, RPTPRR antibody, mPTP213 antibody, protein tyrosine phosphatase, receptor type R antibody, protein tyrosine phosphatase, receptor type, R antibody, protein tyrosine phosphatase, receptor type R L homeolog antibody, protein tyrosine phosphatase, receptor type, r antibody, receptor-type tyrosine-protein phosphatase R antibody, PTPRR antibody, Ptprr antibody, ptprr.L antibody, ptprr antibody, LOC100715069 antibody
- Background
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Synonyms: Ch-1PTPase, Ch1 PTPase, DKFZp781C1038, EC PTP, ECPTP, NC PTPCOM1, NC-PTPCOM1, Protein tyrosine phosphatase Cr1PTPase precursor, Protein tyrosine phosphatase NC PTPCOM1, Protein tyrosine phosphatase PCPTP1, Protein tyrosine phosphatase receptor type R, Protein-tyrosine phosphatase PCPTP1, PTP SL, PTPBR7, PTPRQ, PTPRR, PTPRR_HUMAN, PTPSL, R-PTP-R, Receptor type tyrosine protein phosphatase R, Receptor-type tyrosine-protein phosphatase R.
Background: The protein tyrosine phosphatase (PTP) family of proteins are signaling molecules that regulate processes such as cell growth, cell differentiation, oncogenic transformation and the mitotic cycle. PCPTP1, also known as PTPRR (Receptor-type tyrosine-protein phosphatase R), ECPTP, PTPBR7 or PTPRQ, is a 657 amino acid protein that functions to sequester inactive mitogen-activated protein kinases (MAPKs) to the cytoplasm. Expressed primarily in the brain with weaker expression in other parts of the body, PCPTP1 is a receptor-like molecule that is able to dephosphorylate MAPKs, thereby rendering them inactive. Three isoforms of PCPTP1 exist and are designated alpha, beta and gamma. The alpha form is localized to the cell membrane, while the beta and gamma forms are localized to the perinuclear areas within the cytoplasm.
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