LRRC3B antibody

Catalog No. ABIN1385812

Product Details anti-LRRC3B Antibody

Target: LRRC3B (Leucine Rich Repeat Containing 3B (LRRC3B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRC3B antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LRP15

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for LRRC3B

Target: LRRC3B (Leucine Rich Repeat Containing 3B (LRRC3B))

Alternative Name: LRP15 (LRRC3B Products)

Synonyms: LRP15 antibody, BC019794 antibody, RGD1311897 antibody, LRRC3B antibody, zgc:162270 antibody, leucine rich repeat containing 3B antibody, LRRC3B antibody, Lrrc3b antibody, lrrc3b antibody

Background:

Synonyms: LRP 15, LRP-15, Leucine rich repeat containing 3B, Leucine-rich repeat protein LRP15, Leucine-rich repeat-containing protein 3B, LRC3B_HUMAN, LRRC3B, MGC102927.

Background: Leucine-rich repeats (LRRs) are 20-29 amino acid motifs that mediate protein-protein interactions. The primary function of these motifs is to provide a versatile structural framework for the formation of these protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutation in the genes encoding LRR-containing proteins. The leucine-rich repeat-containing protein 3B (LRRC3B), also designated LRP15, is a 259 amino acid protein that contains 3 LRR repeats. The gene encoding LRRC3B is a tumor suppressor gene that is regulated by DNA methylation. Decreased expression of LRRC3B has been shown in colorectal cancer and gastric cancer, making LRRC3B a candidate marker for those cancers.

Gene ID: 116135