TNFAIP8L2 antibody (AA 10-110)

Catalog No. ABIN1386378

Product Details anti-TNFAIP8L2 Antibody

Target: TNFAIP8L2 (Tumor Necrosis Factor, alpha-Induced Protein 8-Like 2 (TNFAIP8L2))

Binding Specificity: AA 10-110

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNFAIP8L2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TNFAIP8L2/TIPE2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TNFAIP8L2

Target: TNFAIP8L2 (Tumor Necrosis Factor, alpha-Induced Protein 8-Like 2 (TNFAIP8L2))

Alternative Name: TNFAIP8L2/TIPE2 (TNFAIP8L2 Products)

Synonyms: 1810019A08Rik antibody, AW610835 antibody, TIPE2 antibody, RGD1310519 antibody, tnfaip8l2 antibody, TIPE2 A antibody, tnfaip8l2b antibody, zgc:136816 antibody, tipe2 antibody, tnfaip8l2-a antibody, tnfaip8l2-b antibody, TIPE2 B antibody, TNF alpha-induced protein 8-like protein 2 B antibody, TNFAIP8-like protein 2 B antibody, tnfaip8l antibody, tnfaip8l2a antibody, zgc:64074 antibody, tumor necrosis factor, alpha-induced protein 8-like 2 antibody, TNF alpha induced protein 8 like 2 antibody, Tumor necrosis factor, alpha-induced protein 8-like protein 2 antibody, TNF alpha induced protein 8 like 2 L homeolog antibody, tumor necrosis factor, alpha-induced protein 8-like 2a antibody, TNF alpha induced protein 8 like 2 S homeolog antibody, tumor necrosis factor, alpha-induced protein 8-like 2b antibody, Tnfaip8l2 antibody, TNFAIP8L2 antibody, tp8l2 antibody, tnfaip8l2.L antibody, tnfaip8l2a antibody, tnfaip8l2.S antibody, tnfaip8l2b antibody

Background:

Synonyms: Tumor necrosis factor alpha-induced protein 8-like protein 2, Inflammation factor protein 20, TIPE 2, TIPE-2, TNF alpha-induced protein 8-like protein 2, TNFAIP8-like protein 2, TNFAIP8L2, TP8L2_HUMAN, Tumor necrosis factor alpha-induced protein 8-like protein 2, AW610835, FLJ23467.

Background: TNF Alpha-IP 8L2 (tumor necrosis factor, alpha-induced protein 8-like 2), also known as TIPE2, is a 184 amino acid protein that shares 94 % identity with its mouse counterpart and belongs to the TNFAIP8 family. Expressed in spleen, thymus, small intestine and lymph node with lower levels present in colon, lung and skin, TNF Alpha-IP 8L2 plays a role in maintaining immune homeostasis, specifically by acting as a negative regulator of both innate and adaptive immunity. In addition, TNF?IP 8L2 functions as a negative regulator of T-cell receptor function and is thought to promote Fas-induced apoptosis. The gene encoding TNF?IP 8L2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8 % of the human genome.