Glucose-6-Phosphate Dehydrogenase antibody (AA 321-420)

Catalog No. ABIN1386785

Product Details anti-Glucose-6-Phosphate Dehydrogenase Antibody

Target: Glucose-6-Phosphate Dehydrogenase (G6PD)

Binding Specificity: AA 321-420

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glucose-6-Phosphate Dehydrogenase antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human G6PDH

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Glucose-6-Phosphate Dehydrogenase

Target: Glucose-6-Phosphate Dehydrogenase (G6PD)

Alternative Name: G6PDH (G6PD Products)

Synonyms: G6PD1 antibody, g6pd antibody, G6pd antibody, G6pdx antibody, g6pdh antibody, g6pd2 antibody, fj78b06 antibody, wu:fj78b06 antibody, si:dkey-90a13.8 antibody, BA3433 antibody, CORTRD1 antibody, G6PDH antibody, GDH antibody, G28A antibody, G6PD antibody, Gpdx antibody, glucose-6-phosphate dehydrogenase antibody, glucose-6-phosphate 1-dehydrogenase antibody, glucose-6-phosphate 1-dehydrogenase (G6PD) antibody, glucose-6-P dehydrogenase antibody, glucose-6-phosphate dehydrogenase L homeolog antibody, glucose-6-phosphate 1-dehydrogenase Zwf antibody, hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase antibody, glucose-6-phosphate dehydrogenase X-linked antibody, G6PD antibody, g6pd antibody, g6pD antibody, zwf antibody, LOC100120232 antibody, LACBIDRAFT_188936 antibody, G6pd antibody, g6pd.L antibody, CNG03280 antibody, Tb10.70.5200 antibody, H6PD antibody, G6pdx antibody, H6pd antibody

Background:

Synonyms: 6 phosphogluconolactonase, 6-phosphogluconolactonase, 6PGL, H6PD, DKFZp686A01246, G6PD H form, G6PDH, G6PE_HUMAN, GDH, H6PD, GDH/6PGL endoplasmic bunctional protein, Glucose 1 dehydrogenase, Glucose 6 phosphate dehydrogenase salivary, Glucose dehyrogenase, Gpd1, H6pd, Hexose 6 phosphate dehydrogenase, Hexose-6-phosphate dehydrogenase, MGC87643.

Background: H6PD (hexose-6-phosphate dehydrogenase, GDH/6PGL endoplasmic bifunctional protein) is a 789 amino acid protein encoded by the human gene H6PD. The N-terminal section of H6PD belongs to the glucose-6-phosphate dehydrogenase family, while the C-terminal section belongs to the glucosamine/galactosamine-6-phosphate isomerase family, 6-phosphogluconolactonase subfamily. H6PD is responsible primarily for the oxidation of glucose-6-phosphate and glucose. It also oxidizes other hexose-6-phosphates. H6PD catalyzes the conversion of glucose 6-phosphate to 6-phosphogluconolactone within the lumen of the endoplasmic reticulum, thereby generating reduced nicotinamide adenine dinucleotide phosphate. Reduced nicotinamide adenine dinucleotide phosphate is a necessary cofactor for the reductase activity of 11-hydroxysteroid dehydrogenase type 1, which converts hormonally inactive cortisone to active cortisol (in rodents, 11-dehydrocorticosterone to corticosterone).

Gene ID: 9563

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones