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FNDC1 antibody (AA 21-120)

FNDC1 Reactivity: Human IF (cc), IF (p), IHC (p), ELISA, IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1386842
  • Target See all FNDC1 Antibodies
    FNDC1 (Fibronectin Type III Domain Containing Protein 1 (FNDC1))
    Binding Specificity
    AA 21-120
    Reactivity
    Human
    Host
    • 14
    Rabbit
    Clonality
    • 14
    Polyclonal
    Conjugate
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FNDC1 antibody is un-conjugated
    Application
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human FNDC1
    Isotype
    IgG
  • Application Notes
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    FNDC1 (Fibronectin Type III Domain Containing Protein 1 (FNDC1))
    Alternative Name
    FNDC1 (FNDC1 Products)
    Synonyms
    AGS8 antibody, FNDC2 antibody, MEL4B3 antibody, RP11-243O10.2 antibody, bA243O10.1 antibody, dJ322A24.1 antibody, 1110027O12Rik antibody, 1110051A18Rik antibody, mKIAA1866 antibody, fibronectin type III domain containing 1 antibody, FNDC1 antibody, Fndc1 antibody
    Background

    Synonyms: Activation-associated cDNA protein, AGS8, Expressed in synovial lining protein, fibronectin type III domain containing 2, Fibronectin type III domain-containing protein 1, FNDC1, FNDC1_HUMAN, FNDC2, MEL4B3.

    Background: FNDC1, also known as MEL4B3, Ags8, Expressed in synovial lining protein and Activation-associated cDNA protein, is a 1888 amino acid secreted protein that contains five fibronectin type-III domains. FNDC1 is moderately expressed in skeletal muscle, pancreas, heart, kidney, spinal cord, ovary and lung. Expression of FNDC1 is induced in response to hypoxia in ventricular cardiomyocytes. Since FNDC1 interacts with G and G©, it is likely that FNDC1 is an activator for G-protein signaling. Though normally absent in healthy skin, FNDC1 expression is induced by TGF-beta signaling in skin tumors and psoriasis. There are two isoforms of FNDC1 that are produced as a result of alternative splicing events.

    Gene ID
    84624
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