Kininogen-1 Light Chain antibody
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- Target
- Kininogen-1 Light Chain
- Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
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Clonality
- Polyclonal
-
Conjugate
- Un-conjugated
- Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human HMW Kininogen-1 light chain
- Isotype
- IgG
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-
- Application Notes
-
WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
-
- Target
- Kininogen-1 Light Chain
- Synonyms
- BDK antibody, BK antibody, KNG antibody, KINKG antibody, KINKH antibody, Kng1 antibody, Kngk antibody, kininogen 1 antibody, kininogen 2-like 1 antibody, KNG1 antibody, Kng2l1 antibody
- Background
-
Synonyms: Alpha 2 thiol proteinase inhibitor, HMW Kininogen light Chain, Alpha-2-thiol proteinase inhibitor, Fitzgerald factor, High molecular weight kininogen, HMWK, Ile-Ser-Bradykinin, Kallidin I, Kallidin II, Kininogen 1, KNG1, KNG1_HUMAN, Low molecular weight growth-promoting factor, Williams-Fitzgerald-Flaujeac factor.
Background: This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].
- Gene ID
- 3827
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