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TMEM59 antibody (AA 141-240)

TMEM59 Reactivity: Mouse WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1387723
  • Target See all TMEM59 Antibodies
    TMEM59 (Transmembrane Protein 59 (TMEM59))
    Binding Specificity
    • 14
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 141-240
    Reactivity
    • 14
    • 11
    Mouse
    Host
    • 25
    Rabbit
    Clonality
    • 25
    Polyclonal
    Conjugate
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TMEM59 antibody is un-conjugated
    Application
    • 21
    • 12
    • 12
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human,Rat,Dog,Cow,Pig,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human TMEM59
    Isotype
    IgG
    Top Product
    Discover our top product TMEM59 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    TMEM59 (Transmembrane Protein 59 (TMEM59))
    Alternative Name
    TMEM59 (TMEM59 Products)
    Synonyms
    Tmem59 antibody, C1orf8 antibody, HSPC001 antibody, 1110001M20Rik antibody, 3110046P06Rik antibody, AI256529 antibody, D4Ertd20e antibody, MTDCF1 antibody, ORF18 antibody, transmembrane protein 59 antibody, tmem59 antibody, Tmem59 antibody, TMEM59 antibody
    Background

    Synonyms: C1orf8, HSPC001, Liver membrane-bound protein, TMEM59, TMEM59 transmembrane protein 59, TMM59_HUMAN, Transmembrane protein 59.

    Background: TMEM59 is a 144 amino acid protein encoded by a gene mapping to human chromosome 1. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

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