TAS2R7 antibody (AA 121-220) (Biotin)

Catalog No. ABIN1392325

Product Details anti-TAS2R7 Antibody (Biotin)

Target: TAS2R7 (Taste Receptor, Type 2, Member 7 (TAS2R7))

Binding Specificity: AA 121-220

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAS2R7 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TAS2R7/T2R7

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for TAS2R7

Target: TAS2R7 (Taste Receptor, Type 2, Member 7 (TAS2R7))

Alternative Name: TAS2R7/T2R7 (TAS2R7 Products)

Synonyms: T2R7 antibody, TRB4 antibody, t2r1 antibody, t2r7 antibody, trb4 antibody, Patr-T2R7 antibody, taste 2 receptor member 7 antibody, taste receptor, type 2, member 7 antibody, TAS2R7 antibody, tas2r7 antibody

Background:

Synonyms: STC7 4, T2R30, T2R6, T2R7, TA2R7_HUMAN, Tas2r130, Tas2r6, TAS2R7, Taste receptor family B member 4, Taste receptor type 2 member 7, TRB4.

Background: The sense of taste provides animals with valuable information about the quality and nutritional value of food. A family of G protein-coupled receptors are involved in taste perception and include T1R, which is involved in sweet and umami taste perception, and T2R, which is involved in bitter taste perception. Both types of taste receptors couple to various G proteins to initiate signal transduction cascades. Single taste receptor cells express a variety of T2Rs, suggesting that each cell is capable of recognizing multiple tastants. T2R6 (also designatedT2R30, mt2r42, STC 7-4 or taste receptor, type 2, member 130) is an integral membrane receptor protein in mice that may play a role in the perception of bitterness and in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate Alpha-gustducin, mediate PLC-Beta-2 activation and lead to the gating of TRPM5. T2R6 is expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells. The human homolog of T2R6, designated T2R7 (TAS2R7, TRB4 or taste receptor, type 2, member 7) is a G protein-coupled receptor expressed in taste receptor cells of the tongue and palate epithelia.