GBX1 antibody (AA 201-300) (Alexa Fluor 488)

Catalog No. ABIN1392586

Product Details anti-GBX1 Antibody (Alexa Fluor 488)

Target: GBX1 (Gastrulation Brain Homeobox 1 (GBX1))

Binding Specificity: AA 201-300

Reactivity: Mouse, Rat, Chimpanzee

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBX1 antibody is conjugated to Alexa Fluor 488

Application: Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Chimpanzee, Mouse, Rat

Predicted Reactivity: Human,Dog,Sheep,Pig,Chicken,Rabbit,Chimpanzee,Drosophila

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Gbx1

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GBX1

Target: GBX1 (Gastrulation Brain Homeobox 1 (GBX1))

Alternative Name: Gbx1 (GBX1 Products)

Synonyms: Huh-17 antibody, Gbx-1 antibody, CHOX-7 antibody, GBX-1 antibody, cb619 antibody, fj77a06 antibody, wu:fj77a06 antibody, gastrulation brain homeobox 1 antibody, GBX1 antibody, Gbx1 antibody, gbx1 antibody

Background:

Synonyms: Gastrulation and brain specic homeobox protein 1, Gastrulation and brain-specic homeobox protein 1, Gastrulation brain homeo box 1, Gastrulation brain homeobox 1, Gbx1, GBX1_HUMAN, Homeobox protein GBX-1, Homeobox protein GBX1.

Background: The homeobox is DNA sequence that is approximately 180 base pairs long that is involved in all steps of the developmental regulation of animals, fungi and plants, from embryogenesis to cell differentiation. The homeobox encodes a protein domain of about 60 amino acids, called the homeodomain, that can bind to DNA. The gastrulation brain homeobox 1 (GBX1) gene, along with another homeobox gene (EN2), maps to chromosome 7q36, and is expressed in septal and pallidal areas and in the basal forebrain cholinergic system, an area implicated in Alzheimer?s disease. The GBX1 gene encodes the GBX1 protein, which localizes to the nucleus and contains 1 homeobox DNA-binding domain.