SFRS7 antibody (AA 2-70) (Alexa Fluor 488)

Catalog No. ABIN1393132

Product Details anti-SFRS7 Antibody (Alexa Fluor 488)

Target: SFRS7 (Splicing Factor, Arginine/Serine Rich 7 (SFRS7))

Binding Specificity: AA 2-70

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SFRS7 antibody is conjugated to Alexa Fluor 488

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Chicken,Zebrafish

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SFRS7

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SFRS7

Target: SFRS7 (Splicing Factor, Arginine/Serine Rich 7 (SFRS7))

Alternative Name: SFRS7/9G8/SRp20 (SFRS7 Products)

Synonyms: 9G8 antibody, AAG3 antibody, SFRS7 antibody, 35kDa antibody, 9430065L19Rik antibody, NX-96 antibody, Sfrs7 antibody, 9g8 antibody, aag3 antibody, sfrs7 antibody, srsf7 antibody, zgc:114203 antibody, serine and arginine rich splicing factor 7 antibody, serine/arginine-rich splicing factor 7 antibody, serine/arginine-rich splicing factor 7 L homeolog antibody, serine/arginine-rich splicing factor 7b antibody, SRSF7 antibody, Srsf7 antibody, srsf7.L antibody, srsf7b antibody

Background:

Synonyms: 9G8, AAG3, SFRS7, Serine/arginine-rich splicing factor 7, Splicing factor 9G8, Splicing factor, arginine/serine-rich 7, SRSF7

Background: Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway), enhances NXF1-NXT1 RNA-binding activity. RNA-binding is semi-sequence specific.

Gene ID: 6432

UniProt: Q16629