LINGO4 antibody (AA 331-450) (Alexa Fluor 350)

Catalog No. ABIN1393827

Product Details anti-LINGO4 Antibody (Alexa Fluor 350)

Target: LINGO4 (Leucine Rich Repeat and Ig Domain Containing 4 (LINGO4))

Binding Specificity: AA 331-450

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LINGO4 antibody is conjugated to Alexa Fluor 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LINGO4

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for LINGO4

Target: LINGO4 (Leucine Rich Repeat and Ig Domain Containing 4 (LINGO4))

Alternative Name: LINGO4 (LINGO4 Products)

Synonyms: A530050P17Rik antibody, LERN4 antibody, Lrrn6d antibody, RGD1562025 antibody, DAAT9248 antibody, LRRN6D antibody, PRO34002 antibody, zgc:198379 antibody, leucine rich repeat and Ig domain containing 4 antibody, leucine rich repeat and Ig domain containing 4b antibody, Lingo4 antibody, LINGO4 antibody, lingo4b antibody

Background:

Synonyms: Leucine rich repeat and Ig domain containing 4, Leucine rich repeat and immunoglobulin like domain containing nogo receptor interacting protein 4, Leucine rich repeat neuronal protein 6D, LRRN6D, LIGO4_HUMAN.

Background: Lingo-4 is a 593 amino acid single-pass type I membrane protein that contains eleven LRR (leucine-rich) repeats, one Ig-like C2-type (immunoglobulin-like) domain, one LRRCT domain and one LRRNT domain. The gene that encodes Lingo-4 consists of approximately 5,891 bases and maps to human chromosome 1q21.3. Comprising nearly 8 % of the human genome, chromosome 1 spans 260 million base pairs, contains over 3,000 genes and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson?s disease, Gaucher disease, schizophrenia and Usher syndrome.