PCNX antibody (AA 701-800) (Alexa Fluor 647)

Catalog No. ABIN1394172

Product Details anti-PCNX Antibody (Alexa Fluor 647)

Target: PCNX (Pecanex Homolog (PCNX))

Binding Specificity: AA 701-800

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCNX antibody is conjugated to Alexa Fluor 647

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Pecanex

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PCNX

Target: PCNX (Pecanex Homolog (PCNX))

Alternative Name: Pecanex (PCNX Products)

Synonyms: PCNXL1 antibody, 2900024E21Rik antibody, 3526401J03Rik antibody, AF096286 antibody, AI327143 antibody, AI413187 antibody, Pcnxl1 antibody, PCNX antibody, pecanex homolog 1 antibody, pecanex homolog (Drosophila) antibody, pecanex homolog 1 (Drosophila) antibody, pecanex-like protein 3 antibody, PCNX1 antibody, Pcnx antibody, Pcnx1 antibody, LOC100206766 antibody, pcnx1 antibody, pcnx antibody

Background:

Synonyms: PCNXL1, Pecanex homolog, Pecanex like protein 1, PCX1_HUMAN.

Background: Human Pecanex proteins are homologs of the Drosophila Pecanex protein, a maternal-effect neurogenic protein that is involved in normal development of the fly nervous system. Three human Pecanex homologs exist, designated Pecanex, Pecanex 2, also known as PCNXL2 (pecanex-like 2), and Pecanex 3. Pecanex 2 is a 2,137 amino acid multi-pass membrane protein that exists as five alternatively spliced isoforms characterized by high mutational frequencies and biallelic mutations in colorectal tumors, thereby likely functioning as a target gene in these tumors. Pecanex 2 is encoded by a gene that maps to human chromosome 1q42.2, which is linked to an inherited microduplication. This microduplication that includes Pecanex 2 may play a role in autism and mild mental retardation.

Gene ID: 22990