NSG2 antibody (AA 31-140) (Biotin)

Catalog No. ABIN1394791

This Rabbit Polyclonal antibody specifically detects NSG2 in IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for NSG2 antibody (AA 31-140) (Biotin) (ABIN1394791)

Target: NSG2 (HMP19) (Neuron-Specific Protein Family Member 2 (HMP19))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NSG2 antibody is conjugated to Biotin

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-NSG2 Antibody (Biotin)

Binding Specificity: AA 31-140

Purpose: NSG2 Polyclonal Antibody, Biotin Conjugated

Predicted Reactivity: Human,Mouse,Rat,Cow,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NSG2/HMP19

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for NSG2

Target: NSG2 (HMP19) (Neuron-Specific Protein Family Member 2 (HMP19))

Alternative Name: NSG2

Background:

Synonyms: HMP19, Neuron-specic protein family member 2, Nsg2, NSG2_HUMAN, Protein p19.

Background: With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6 % of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.