HCV RdRP antibody (AA 2501-2600) (Alexa Fluor 555)

Catalog No. ABIN1396816

Product Details anti-HCV RdRP Antibody (Alexa Fluor 555)

Target: HCV RdRP (Hepatitis C Virus RNA-Directed RNA Polymerase (HCV RdRP))

Binding Specificity: AA 2501-2600

Reactivity: Hepatitis C Virus (HCV), Virus

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HCV RdRP antibody is conjugated to Alexa Fluor 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Virus

Cross-Reactivity (Details): HCV

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from Hepatitis C Virus RNA-directed RNA polymerase

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for HCV RdRP

Target: HCV RdRP (Hepatitis C Virus RNA-Directed RNA Polymerase (HCV RdRP))

Alternative Name: Hepatitis C Virus RNA-directed RNA polymerase (HCV RdRP Products)

Target Type: Viral Protein

Background:

Synonyms: RNA-directed RNA polymerase, p68, RNA dependent RNA polymerase.

Background: The RNA directed RNA polymerase is also known as non-structural protein NS5B. NS5B is a 65 kDa protein that resembles other viral RNA polymerases. Hepatitis C virus (HCV) replication is thought to occur in membrane bound replication complexes. These complexes transcribe the positive strand and the resulting minus strand is used as a template for the synthesis of genomic RNA. There are two viral proteins involved in the reaction, NS3 and NS5B