BPIFC antibody (Alexa Fluor 350)

Catalog No. ABIN1399005

Product Details anti-BPIFC Antibody (Alexa Fluor 350)

Target: BPIFC (BPI Fold Containing Family C (BPIFC))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BPIFC antibody is conjugated to Alexa Fluor 350

Application: Western Blotting (WB)

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BPIL2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for BPIFC

Target: BPIFC (BPI Fold Containing Family C (BPIFC))

Alternative Name: BPIL2 (BPIFC Products)

Synonyms: BPIL2 antibody, 4732454E24 antibody, Bpil2 antibody, BPI fold containing family C antibody, BPI fold containing family C, member B antibody, BPIFC antibody, BPIFCB antibody, Bpifc antibody

Background:

Synonyms: BPIL 2, BPIL-2, bactericidal/permeability increasing protein like 2, BPC_HUMAN.

Background: Members of the bactericidal/permeability-increasing protein family have antimicrobial properties and bind lipophilic substances, therefore targeting gram-negative bacteria. The bactericidal permeability increasing protein (BPI) is an antibacterial and endotoxin-neutralizing molecule that is abundant in the granules of polymorphonuclear leukocytes (neutrophil granules). Sharing structural and sequence homologies with BPI, BPIL2 (Bactericidal/permeability-increasing protein-like 2) is a 507 amino acid secreted protein that contains the family?s common conserved feature of two cysteine residues that are critical for protein function. While BPIL2 is expressed in the basal layer of inflamed epidermis from psoriasis patients, it is not detected in normal skin.

Gene ID: 254240

UniProt: Q8NFQ6