BEND4 antibody (AA 351-450) (Alexa Fluor 488)

Catalog No. ABIN1399090

Product Details anti-BEND4 Antibody (Alexa Fluor 488)

Target: BEND4 (BEN Domain Containing 4 (BEND4))

Binding Specificity: AA 351-450

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BEND4 antibody is conjugated to Alexa Fluor 488

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BEND4/CCDC4

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for BEND4

Target: BEND4 (BEN Domain Containing 4 (BEND4))

Alternative Name: BEND4 (BEND4 Products)

Synonyms: CCDC4 antibody, D330027G24Rik antibody, EG666938 antibody, BEN domain containing 4 antibody, BEND4 antibody, Bend4 antibody

Background:

Synonyms: BEN domain containing 4, BEN domain containing protein 4, BEN domain-containing protein 4, Bend4, BEND4_HUMAN, CCDC4, Coiled coil domain containing 4, Coiled coil domain containing protein 4, Coiled-coil domain-containing protein 4, FLJ35632, FLJ43965, MGC157807, MGC157808.

Background: BEND4 is a 530 amino acid protein that contains a BEN domain. BEND4 exists as five alternatively spiced isoforms and is considered a complete proteome. BEN domain mediates proteinDNA and proteinprotein interactions during chromatin organization and transcription. BEN domain may play a role in organization of viral DNA during replication or transcription. The BEND4 gene maps to human chromosome 4p13. Representing approximately 6 % of the human genome, chromosome 4 contains nearly 900 genes. Chromosome 4 reportedly contains the largest gene deserts (regions of the genome with no protein encoding genes) and has one of the two lowest recombination frequencies of the human chromosomes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer.