OxLDL antibody (Biotin)

Catalog No. ABIN1399813

Product Details anti-OxLDL Antibody (Biotin)

Target: OxLDL (Oxidized Low Density Lipoprotein (OxLDL))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OxLDL antibody is conjugated to Biotin

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse

Purification: Purified by Protein A.

Immunogen: Cu2+ oxidized low density lipoprotein

Isotype: IgG

Application Details

Application Notes: IHC-P(1:100-500)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for OxLDL

Target: OxLDL (Oxidized Low Density Lipoprotein (OxLDL))

Alternative Name: Ox-LDL (OxLDL Products)

Background:

Synonyms: ox-LDL: Cu2SO4 oxidized low density lipoprotein, oxidized low density lipoprotein, Low density lipoprotein, MDA oxidized LDL, MDA oxidized low density lipoprotein.

Background: Low-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood. LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearence of cholesterol from the circulation. In atherosclerotic lesions oxidatively modified LDL is found and oxidized LDL is specifically recognized and ingested by macrophages via scavenger receptor A and CD36. Oxidized LDL may be a marker of atherosclerosis but the precise changes in oxidized LDL are not well described. Low-density lipoprotein oxidised with Cu2SO4.