TLR8 antibody (AA 451-550) (AbBy Fluor® 555)

Catalog No. ABIN1400165

The Rabbit Polyclonal anti-TLR8 antibody is suitable to detect TLR8 in samples from Human. It has been validated for WB, IF (cc) and IF (p).

Quick Overview for TLR8 antibody (AA 451-550) (AbBy Fluor® 555) (ABIN1400165)

Target: TLR8 (Toll-Like Receptor 8 (TLR8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR8 antibody is conjugated to AbBy Fluor® 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-TLR8 Antibody (AbBy Fluor® 555)

Binding Specificity: AA 451-550

Purpose: TLR8 Polyclonal Antibody, AbBy Fluor-555 Conjugated

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TLR 8

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TLR8

Target: TLR8 (Toll-Like Receptor 8 (TLR8))

Alternative Name: TLR8

Background:

Synonyms: Toll-like receptor 8, TLR8, UNQ249/PRO286

Background: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.

Gene ID: 51311

UniProt: Q9NR97

Pathways: TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades