TLR8 antibody (AA 723-825)

Catalog No. ABIN526632

Cited in 1 publication. The Mouse Monoclonal anti-TLR8 antibody (Clone 4C6) (ABIN526632) specifically detects TLR8 in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for TLR8 antibody (AA 723-825) (ABIN526632)

Target: TLR8 (Toll-Like Receptor 8 (TLR8))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TLR8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 4C6

Product Details anti-TLR8 Antibody

Binding Specificity: AA 723-825

Purpose: Mouse monoclonal antibody raised against a partial recombinant TLR8.

Sequence: RISHLPSGFL SEVSSLKHLD LSSNLLKTIN KSALETKTTT KLSMLELHGN PFECTCDIGD FRRWMDEHLN VKIPRLVDVI CASPGDQRGK SIVSLELTTC VSD

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: TLR8 (NP_619542, 723 a.a. ~ 825 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-TLR8 antibody (ABIN526632)

Cervantes, Dunham-Ems, La Vake, Petzke, Sahay, Sellati, Radolf, Salazar: "Phagosomal signaling by Borrelia burgdorferi in human monocytes involves Toll-like receptor (TLR) 2 and TLR8 cooperativity and TLR8-mediated induction of IFN-beta." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 9, pp. 3683-8, (2011) (PubMed).

Target Details for TLR8

Target: TLR8 (Toll-Like Receptor 8 (TLR8))

Alternative Name: TLR8

Background: Full Gene Name: toll-like receptor 8
Synonyms: CD288,MGC119599,MGC119600

Gene ID: 51311

NCBI Accession: NM_138636

Pathways: TLR Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades