PDXK antibody (Alexa Fluor 647)

Catalog No. ABIN1400466

Product Details anti-PDXK Antibody (Alexa Fluor 647)

Target: PDXK (Pyridoxal Kinase (PDXK))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDXK antibody is conjugated to Alexa Fluor 647

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PDXK

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PDXK

Target: PDXK (Pyridoxal Kinase (PDXK))

Alternative Name: PDXK (PDXK Products)

Synonyms: C21orf124 antibody, C21orf97 antibody, PKH antibody, PNK antibody, 2310036D04Rik antibody, AA119688 antibody, C77999 antibody, Pdxk antibody, PSPTO5521 antibody, DDBDRAFT_0190079 antibody, DDBDRAFT_0191114 antibody, DDB_0190079 antibody, DDB_0191114 antibody, ATSOS4 antibody, K18L3.1 antibody, K18L3_1 antibody, SALT OVERLY SENSITIVE 4 antibody, pdxk antibody, si:dkey-263m10.2 antibody, si:dz69g10.1 antibody, cb1056 antibody, pdxkl antibody, si:dkey-281i8.2 antibody, wu:fa55a03 antibody, wu:fb10c12 antibody, zgc:101900 antibody, pyridoxal kinase antibody, pyridoxal (pyridoxine, vitamin B6) kinase antibody, Pyridoxal kinase antibody, pfkB-like carbohydrate kinase family protein antibody, pyridoxal (pyridoxine, vitamin B6) kinase b antibody, pyridoxal (pyridoxine, vitamin B6) kinase a antibody, PDXK antibody, Pdxk antibody, pdxY antibody, pdxK antibody, Bphyt_1541 antibody, pykA antibody, Kfla_4736 antibody, Kvar_1290 antibody, Mrub_2507 antibody, BC1002_1103 antibody, Fbal_1661 antibody, Lbys_0710 antibody, Intca_0131 antibody, Deima_3190 antibody, Mesop_1158 antibody, LOC100283562 antibody, pdxk antibody, SOS4 antibody, pdxkb antibody, pdxka antibody

Background:

Synonyms: PDXK.1, pdxK, PDXK_HUMAN, PKH, PNK, Pyridoxal kinase, Pyridoxamine kinase, Pyridoxine kinase, Vitamin B6 kinase.

Background: Pyridoxal kinase belongs to the pyridoxine kinase family and phosphorylates vitamin B6, a step necessary for the conversion of vitamin B6 to pyridoxal 5? phosphate (PLP), the active form of vitamin B6. PLP acts as a coenzyme and functions to maintain homeostasis. Pyridoxal kinase is a 312-amino acid cytoplasmic protein that may act as a homodimer and is expressed ubiquitously. There are three known isoforms of pyridoxal kinase, and isoform 3 expression is observed in adult testis and spermatozoa. The optimum pH for pyridoxal kinase is between 5.5 and 6.0. PDXK, the gene that encodes the pyridoxal kinase protein, maps to chromosome 21q22.3 and may be a candidate gene for autoimmune polyglandular disease type 1, a genetic disorder that has been mapped to the same region on chromosome 21.

Gene ID: 8566