FBXO21 antibody (Alexa Fluor 488)
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- Target See all FBXO21 Antibodies
- FBXO21 (F-Box Protein 21 (FBXO21))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FBXO21 antibody is conjugated to Alexa Fluor 488
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human FBXO21
- Isotype
- IgG
- Top Product
- Discover our top product FBXO21 Primary Antibody
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anti-F-Box Protein 21 (FBXO21) antibody
FBXO21 Reactivity: Human, Mouse, Rat, Dog, Monkey WB, IHC, IF, FACS, IHC (p) Host: Mouse Monoclonal 2C7 unconjugated
anti-F-Box Protein 21 (FBXO21) antibodyFBXO21 Reactivity: Human, Mouse, Rat, Monkey WB, IHC, IF, FACS, IHC (p) Host: Mouse Monoclonal 5H4 unconjugated
anti-F-Box Protein 21 (FBXO21) (AA 440-621) antibodyFBXO21 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-F-Box Protein 21 (FBXO21) (AA 474-501), (C-Term) antibodyFBXO21 Reactivity: Mouse WB, IHC (p) Host: Rabbit Polyclonal RB18234 unconjugated
anti-F-Box Protein 21 (FBXO21) antibodyFBXO21 Reactivity: Human, Mouse, Rat WB, IF Host: Rabbit Polyclonal unconjugated
anti-F-Box Protein 21 (FBXO21) (AA 74-123) antibodyFBXO21 Reactivity: Human, Mouse, Rat, Dog, Monkey, Rabbit, Cow, Hamster, Pig, Bat WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-F-Box Protein 21 (FBXO21) (AA 1-621) antibodyFBXO21 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-F-Box Protein 21 (FBXO21) (N-Term) antibodyFBXO21 Reactivity: Human, Mouse, Rat, Dog, Rabbit, Guinea Pig, Cow, Saccharomyces cerevisiae WB, IHC Host: Rabbit Polyclonal unconjugated
anti-F-Box Protein 21 (FBXO21) (C-Term) antibodyFBXO21 Reactivity: Human, Mouse, Rat, Dog, Rabbit, Guinea Pig, Horse WB, IHC Host: Rabbit Polyclonal unconjugated
anti-F-Box Protein 21 (FBXO21) (AA 474-503), (C-Term) antibodyFBXO21 Reactivity: Human, Mouse WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- IF(IHC-P) 1:50-200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- FBXO21 (F-Box Protein 21 (FBXO21))
- Alternative Name
- FBXO21 (FBXO21 Products)
- Synonyms
- FBX21 antibody, 2810425J22Rik antibody, AU016673 antibody, mKIAA0875 antibody, si:ch211-42a13.2 antibody, F-box protein 21 antibody, FBXO21 antibody, Fbxo21 antibody, fbxo21 antibody
- Background
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Synonyms: F box only protein 21, F box protein 21, F-box only protein 21, FBX21, FBX21_HUMAN, Fbxo21, FLJ90233, KIAA0875, MGC26682.
Background: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Has some glucocorticoid receptor-responsive activity.
- Gene ID
- 23014
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