AXDND1 antibody (Alexa Fluor 488)

Catalog No. ABIN1404604

Product Details anti-AXDND1 Antibody (Alexa Fluor 488)

Target: AXDND1 (Axonemal Dynein Light Chain Domain Containing 1 (AXDND1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AXDND1 antibody is conjugated to Alexa Fluor 488

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C1orf125

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for AXDND1

Target: AXDND1 (Axonemal Dynein Light Chain Domain Containing 1 (AXDND1))

Alternative Name: C1orf125 (AXDND1 Products)

Synonyms: C1orf125 antibody, RP11-215I23.2 antibody, 9430070O13Rik antibody, Gm979 antibody, axonemal dynein light chain domain containing 1 antibody, AXDND1 antibody, Axdnd1 antibody

Background:

Synonyms: axonemal dynein light chain domain containing 1, AXDN1_HUMAN, AXDND1, Axonemal dynein light chain domain-containing protein 1, DKFZp686H1423, hypothetical protein LOC126859, RP11-215I23.2.

Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf125 gene product has been provisionally designated C1orf125 pending further characterization.

Gene ID: 126859