TCEANC2 antibody (Alexa Fluor 350)

Catalog No. ABIN1404675

Product Details anti-TCEANC2 Antibody (Alexa Fluor 350)

Target: TCEANC2 (Transcription Elongation Factor A (SII) N-Terminal and Central Domain Containing 2 (TCEANC2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCEANC2 antibody is conjugated to Alexa Fluor 350

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C1orf83

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TCEANC2

Target: TCEANC2 (Transcription Elongation Factor A (SII) N-Terminal and Central Domain Containing 2 (TCEANC2))

Alternative Name: C1orf83 (TCEANC2 Products)

Synonyms: C1orf83 antibody, RP4-758J24.3 antibody, 2210010B22Rik antibody, 2210012G02Rik antibody, 6330404A07Rik antibody, AU015593 antibody, Tdeanc2 antibody, si:dkey-63k7.9 antibody, tcean2 antibody, transcription elongation factor A N-terminal and central domain containing 2 antibody, transcription elongation factor A (SII) N-terminal and central domain containing 2 antibody, TCEANC2 antibody, Tceanc2 antibody, tceanc2 antibody

Background:

Synonyms: chromosome 1 open reading frame 83, FLJ32112, FLJ39169, hypothetical protein LOC127428, Uncharacterized protein C1orf83, TEAN2_HUMAN.

Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf83 gene product has been provisionally designated C1orf83 pending further characterization. There are two isoforms of C1orf83 that are produced as a result of alternative splicing events.

Gene ID: 127428