C11orf24 antibody (Alexa Fluor 488)

Catalog No. ABIN1405546

Product Details anti-C11orf24 Antibody (Alexa Fluor 488)

Target: C11orf24 (Chromosome 11 Open Reading Frame 24 (C11orf24))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C11orf24 antibody is conjugated to Alexa Fluor 488

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C11orf24

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for C11orf24

Target: C11orf24 (Chromosome 11 Open Reading Frame 24 (C11orf24))

Alternative Name: C11orf24 (C11orf24 Products)

Synonyms: DM4E3 antibody, AI256204 antibody, chromosome 11 open reading frame 24 antibody, RIKEN cDNA 1810055G02 gene antibody, similar to RIKEN cDNA 1810055G02 antibody, C11orf24 antibody, 1810055G02Rik antibody, RGD1311946 antibody

Background:

Synonyms: CK024_HUMAN, Protein DM4E3, Uncharacterized protein C11orf24.

Background: C11orf24, also known as DM4E3, is a 449 amino acid single-pass type I membrane protein that is expressed in brain, lung, skeletal muscle, kidney, spleen, prostate, testis, ovary and small intestine, with highest expression in heart, placenta, liver, pancreas and colon, and low expression in thymus and leukocytes. C11orf24 is encoded by a gene located on human chromosome 11, which consists of approximately 135 million base pairs and 1,400 genes. Chromosome 11 makes up around 4 % of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and _ thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.

Gene ID: 53838