LRRC75B/FAM211B antibody (Alexa Fluor 488)

Catalog No. ABIN1405786

Product Details anti-LRRC75B/FAM211B Antibody (Alexa Fluor 488)

Target: LRRC75B/FAM211B (C22orf36) (Chromosome 22 Open Reading Frame 36 (C22orf36))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRC75B/FAM211B antibody is conjugated to Alexa Fluor 488

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C22orf36

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for LRRC75B/FAM211B

Target: LRRC75B/FAM211B (C22orf36) (Chromosome 22 Open Reading Frame 36 (C22orf36))

Alternative Name: C22orf36 (C22orf36 Products)

Synonyms: C22orf36 antibody, AI646023 antibody, leucine rich repeat containing 75B antibody, LRRC75B antibody, Lrrc75b antibody

Background:

Synonyms: C22orf36, Leucine-rich repeat-containing protein C22orf36, chromosome 22 open reading frame 36, LRC6X_HUMAN.

Background: C22orf36 is a 315 amino acid protein that contains two LRR (leucine-rich) repeats and exists as two alternatively spliced isoforms. C22orf36 is encoded by a gene located on human chromosome 22, which contains over 500 genes and about 49 million bases. As the second smallest human chromosome, chomosome 22 contains a wide variety of genes with numerous functions. Phelan-McDermid syndrome, Neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein, BCR-Abl, a potent cell proliferation activator found in several types of leukemia.

Gene ID: 388886