LZIC antibody (AA 31-130) (HRP)

Catalog No. ABIN1410350

Product Details anti-LZIC Antibody (HRP)

Target: LZIC (Leucine Zipper and CTNNBIP1 Domain Containing (LZIC))

Binding Specificity: AA 31-130

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LZIC antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LZIC

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for LZIC

Target: LZIC (Leucine Zipper and CTNNBIP1 Domain Containing (LZIC))

Alternative Name: LZIC (LZIC Products)

Synonyms: 1810030J04Rik antibody, AW047580 antibody, zgc:92310 antibody, leucine zipper and CTNNBIP1 domain containing antibody, LZIC antibody, Lzic antibody, lzic antibody

Background:

Synonyms: Leucine zipper and CTNNBIP1 domain containing protein, Leucine zipper and ICAT homologous domain containing protein, leucine zipper domain and ICAT homologous domain containing, LZIC antibodyprotein LZIC, LZIC_HUMAN.

Background: LZIC is a 190 amino acid protein that belongs to the CTNNBIP1 family. Ubiquitously expressed, LZIC is found at highest levels in kidney and is upregulated in a few gastric carcinomas. The gene encoding LZIC maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8 % of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson?s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.