P2RY8 antibody (AA 131-230) (HRP)

Catalog No. ABIN1412894

Product Details anti-P2RY8 Antibody (HRP)

Target: P2RY8 (Purinergic Receptor P2Y, G-Protein Coupled, 8 (P2RY8))

Binding Specificity: AA 131-230

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P2RY8 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human P2Y8

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for P2RY8

Target: P2RY8 (Purinergic Receptor P2Y, G-Protein Coupled, 8 (P2RY8))

Alternative Name: P2Y8 (P2RY8 Products)

Synonyms: P2Y8 antibody, P2Y purinoceptor 8 antibody, P2Y receptor family member 8 antibody, purinergic receptor P2Y8 antibody, p2ry8 antibody, P2RY8 antibody

Background:

Synonyms: P2RY8, P2Y receptor family member 8, P2RY8_HUMAN, P2Y purinoceptor 8, P2Y8, Purinergic receptor P2Y G protein coupled 8.

Background: G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G-protein coupled receptors translate extracellular signals into intracellular signals (G-protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. P2RY8 (purinergic receptor P2Y, G-protein coupled, 8), also known as P2Y8, is a 359 amino acid multi-pass membrane protein that localizes to the cell membrane and belongs to the G protein-coupled receptor family. Expressed at low levels in lung, heart and kidney, P2RY8 may function as a receptor for purines that are coupled to G proteins and may also play a role in mental retardation.

Gene ID: 286530

UniProt: Q86VZ1