SUMO1 antibody (AA 98-158) (Cy7)

Catalog No. ABIN1416422

The Rabbit Polyclonal anti-SUMO1 antibody is suitable to detect SUMO1 in samples from Human. It has been validated for WB, IF (cc) and IF (p).

Quick Overview for SUMO1 antibody (AA 98-158) (Cy7) (ABIN1416422)

Target: SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUMO1 antibody is conjugated to Cy7

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-SUMO1 Antibody (Cy7)

Binding Specificity: AA 98-158

Purpose: UBE2I Polyclonal Antibody, Cy7 Conjugated

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human UBE2I

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SUMO1

Target: SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))

Alternative Name: SUMO-1

Background:

Synonyms: p18, SUMO 1 protein ligase, SUMO conjugating enzyme UBC9, SUMO-1 conjugating enzyme, SUMO-1-protein ligase, SUMO-conjugating enzyme UBC9, SUMO-protein ligase, SUMO1 protein ligase, UBC9, UBC9_HUMAN, UBCE9, Ube2i, Ubiquitin carrier protein 9, Ubiquitin carrier protein, Ubiquitin carrier protein I, Ubiquitin conjugating enzyme 9, Ubiquitin conjugating enzyme UbcE2A, Ubiquitin like protein SUMO 1 conjugating enzyme, Ubiquitin protein ligase E2I, Ubiquitin-conjugating enzyme E2 I, Ubiquitin-protein ligase I.

Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

Gene ID: 7329

UniProt: P63279

Pathways: M Phase, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, Ubiquitin Proteasome Pathway