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FBXW4 antibody (AA 171-270) (HRP)

FBXW4 Reactivity: Rat ELISA, IHC (p) Host: Rabbit Polyclonal HRP
Catalog No. ABIN1416682
  • Target See all FBXW4 Antibodies
    FBXW4 (F-Box and WD Repeat Domain Containing 4 (FBXW4))
    Binding Specificity
    • 14
    • 14
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 171-270
    Reactivity
    • 33
    • 11
    • 10
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Rat
    Host
    • 34
    • 2
    Rabbit
    Clonality
    • 36
    Polyclonal
    Conjugate
    • 18
    • 5
    • 4
    • 3
    • 3
    • 3
    This FBXW4 antibody is conjugated to HRP
    Application
    • 28
    • 28
    • 9
    • 3
    • 3
    • 3
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Cross-Reactivity
    Rat
    Predicted Reactivity
    Human,Mouse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SHFM3
    Isotype
    IgG
    Top Product
    Discover our top product FBXW4 Primary Antibody
  • Application Notes
    IHC-P 1:200-400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handling Advice
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    FBXW4 (F-Box and WD Repeat Domain Containing 4 (FBXW4))
    Alternative Name
    SHFM3 (FBXW4 Products)
    Synonyms
    dac antibody, hag antibody, hagoromo antibody, wu:fk63g06 antibody, FBXW4 antibody, DAC antibody, FBW4 antibody, FBWD4 antibody, SHFM3 antibody, SHSF3 antibody, Dac antibody, Fbw4 antibody, dactylin antibody, dactylyn antibody, F-box and WD repeat domain containing 4 antibody, F-box and WD-40 domain protein 4 antibody, fbxw4 antibody, FBXW4 antibody, Fbxw4 antibody
    Background

    Synonyms: DAC, Dactylin, F box and WD 40 domain containing protein 4, F box and WD 40 domain protein 4, F box and WD repeat domain containing 4, F box/WD repeat containing protein 4, F box/WD repeat protein 4, F-box and WD-40 domain-containing protein 4, F-box/WD repeat-containing protein 4, FBW 4, FBW4, FBWD 4, FBWD4, FBXW 4, FBXW4, FBXW4_HUMAN, SHFM 3, SHSF 3, SHSF3, Split hand/foot malformation ectrodactyly type.

    Background: Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathways crucial for normal limb development. May participate in Wnt signaling.Involvement in disease:Defects in FBXW4 are a cause of split-hand/foot malformation type 3 (SHFM3) . SHFM3 is an autosomal dominant disorder characterized by hypoplasia/aplasia of the central digits with fusion of the remaining digits.

    Gene ID
    6468
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