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ZNRF3 antibody (AA 120-165) (Cy7)

ZNRF3 Reactivity: Human, Mouse, Rat IF (p) Host: Rabbit Polyclonal Cy7
Catalog No. ABIN1418942
  • Target See all ZNRF3 Antibodies
    ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))
    Binding Specificity
    • 14
    • 5
    • 1
    • 1
    • 1
    AA 120-165
    Reactivity
    Human, Mouse, Rat
    Host
    • 24
    Rabbit
    Clonality
    • 24
    Polyclonal
    Conjugate
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ZNRF3 antibody is conjugated to Cy7
    Application
    • 12
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ZNRF3
    Isotype
    IgG
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    Discover our top product ZNRF3 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))
    Alternative Name
    ZNRF3 (ZNRF3 Products)
    Synonyms
    BK747E2.3 antibody, RNF203 antibody, AA591877 antibody, BC019575 antibody, Gm1167 antibody, zinc and ring finger 3 antibody, Znrf3 antibody, ZNRF3 antibody
    Background

    Synonyms: RNF203, BK747E2.3, E3 ubiquitin-protein ligase ZNRF3, RING finger protein 203, Zinc/RING finger protein 3, ZNRF3, KIAA1133

    Background: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.

    Gene ID
    84133
    UniProt
    Q9ULT6
    Pathways
    WNT Signaling
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