ADRM1 antibody (C-Term)

Catalog No. ABIN1449910

Product Details anti-ADRM1 Antibody

Target: ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADRM1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QLGPLMCQFG LPAEAVEAAN KGDVEAFAKA MQNNAKPEQK EGDTKDKKDE

Cross-Reactivity (Details): Species reactivity (expected):Mouse, RatSpecies reactivity (tested):Human

Purification: Purified using peptide immunoaffinity column

Immunogen: Synthetic peptide directed towards the C terminal of human ADRM1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Target Details for ADRM1

Target: ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))

Alternative Name: ADRM1 / GP110 (Adrm1 Products)

Synonyms: arm-1 antibody, gp110 antibody, rpn13 antibody, xoom antibody, ADRM1 antibody, adrm1 antibody, ARM-1 antibody, ARM1 antibody, GP110 antibody, 1110063P18Rik antibody, 2510006J17Rik antibody, AA408205 antibody, AU043535 antibody, Arm1 antibody, Gp110 antibody, Rpn13 antibody, adrm1a antibody, adrm1b antibody, fa12d09 antibody, wu:fa10g10 antibody, wu:fa12d09 antibody, zgc:56107 antibody, zgc:77256 antibody, adhesion regulating molecule 1 antibody, ADRM1 antibody, 19S proteasome regulatory subunit antibody, ADRM1 protein antibody, adrm1 antibody, ADRM1 antibody, CpipJ_CPIJ002929 antibody, SJAG_04211 antibody, Adrm1 antibody

Background: ADRM1 functions as a proteasomal ubiquitin receptor and recruits the deubiquitinating enzyme UCHL5 at the 26S proteasome and promotes its activity. The PH domain mediates interactions with PSMD1 and ubiquitin. Preferential binding to the proximal subunit of K48-linked diubiquitin allows UCHL5 access to the distal subunit.Synonyms: 110 kDa cell membrane glycoprotein, Adhesion-regulating molecule 1, Proteasomal ubiquitin receptor ADRM1, Proteasome regulatory particle non-ATPase 13, Rpn13 homolog

Gene ID: 11047

NCBI Accession: NP_008933

Pathways: Positive Regulation of Endopeptidase Activity