LNPEP antibody (C-Term)

Catalog No. ABIN1449971

The Rabbit Polyclonal anti-LNPEP antibody has been validated for WB, IF and EIA. It is suitable to detect LNPEP in samples from Human.

Quick Overview for LNPEP antibody (C-Term) (ABIN1449971)

Target: LNPEP (Leucyl/cystinyl Aminopeptidase (LNPEP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LNPEP antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-LNPEP Antibody

Binding Specificity: C-Term

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid synthetic peptide near the carboxy terminus of Human LNPEP

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for LNPEP

Target: LNPEP (Leucyl/cystinyl Aminopeptidase (LNPEP))

Alternative Name: LNPEP

Background: LNPEP, also known as insulin-responsive aminopeptidase (IRAP), was initially identified as an abundant protein that is associated with specialized endosomes termed GLUT4 storage vesicles (GSVs) in adipocytes. The luminal domain of LNPEP contains an aminopeptidase activity that is involved in peptide hormone processing and antigenic peptide processing. LNPEP is also a key regulator of GLUT4 trafficking by controlling the sorting of GLUT4 from endosomes to the GSVs.Synonyms: Cystinyl aminopeptidase, EC=3.4.11.3, IRAP, Insulin-regulated membrane aminopeptidase, Insulin-responsive aminopeptidase, LNPEP, Leucyl-cystinyl aminopeptidase, OTASE, Oxytocinase, P-LAP, Placental leucine aminopeptidase

Molecular Weight: 113 kDa

Gene ID: 4012

NCBI Accession: NP_005566

Pathways: Regulation of long-term Neuronal Synaptic Plasticity