Presenilin 2 antibody (pSer330)

Catalog No. ABIN1450368

This anti-Presenilin 2 antibody is a Rabbit Polyclonal antibody detecting Presenilin 2 in ELISA and IHC. Suitable for Human, Rat and Mouse.

Quick Overview for Presenilin 2 antibody (pSer330) (ABIN1450368)

Target: Presenilin 2 (PSEN2) (Presenilin 2 (Alzheimer Disease 4) (PSEN2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Presenilin 2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-Presenilin 2 Antibody

Binding Specificity: AA 296-345, pSer330

Specificity:

Presenilin 2 (Phospho-Ser330) Antibody detects endogenous levels of Presenilin 2 only when phosphorylated at Ser330.

PhosphorylationH:S330, M:S330, R:S330

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Immunogen: The antiserum was produced against synthesized peptide derived from human Presenilin 2 around the phosphorylation site of Ser330.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 ELISA: 1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Target Details for Presenilin 2

Target: Presenilin 2 (PSEN2) (Presenilin 2 (Alzheimer Disease 4) (PSEN2))

Alternative Name: Presenilin 2

Background:

Synonyms: AD3LP, AD4, AD4H, AD5, ALG-3, ALG3, Alzheimer disease 4 homolog, E5-1, PS-2, PS2, PSN2, PSNL2, STM-2, STM2, presenilin 2

NCBI Gene Symbol: PSEN2

Molecular Weight: 50 kDa

Gene ID: 5664

OMIM: 600759

UniProt: P49810

Pathways: Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway