Retinoblastoma Protein (Rb) antibody (pSer788)
Quick Overview for Retinoblastoma Protein (Rb) antibody (pSer788) (ABIN1450410)
Target
See all Retinoblastoma Protein (Rb) (Rb Protein) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 756-805, pSer788
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Purpose
- Rb (phospho Ser788) Antibody
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Specificity
- Phospho-Rb (S788) Polyclonal Antibody detects endogenous levels of Rb protein only when phosphorylated at S788.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- The antiserum was produced against synthesized peptide derived from human Retinoblastoma around the phosphorylation site of Ser788. AA range:756-805
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Isotype
- IgG
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anti-Retinoblastoma Protein (Rb Protein) (C-Term) antibody
Rb Protein Reactivity: Human, Mouse, Rat WB, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (pThr826) antibodyRb Protein Reactivity: Human, Mouse, Rat WB, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (pSer807) antibodyRb Protein Reactivity: Human, Mouse, Rat WB, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (pSer780) antibodyKD Validated Rb Protein Reactivity: Human WB, FACS Host: Rabbit Monoclonal 25GB3375 unconjugated Recombinant Antibody
anti-Retinoblastoma Protein (Rb Protein) (pSer807) antibodyKD Validated Rb Protein Reactivity: Human WB, FACS Host: Rabbit Monoclonal 25GB3245 unconjugated Recombinant Antibody
anti-Retinoblastoma Protein (Rb Protein) (pSer811) antibodyRb Protein Reactivity: Human IHC, ELISA, IF, DB Host: Rabbit Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (AA 858-886) antibodyRb Protein Reactivity: Human WB, IHC, ELISA, FACS Host: Rabbit Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (AA 586-615) antibodyRb Protein Reactivity: Human WB, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Retinoblastoma Protein (Rb Protein) (Cleavage Site) antibodyRb Protein Reactivity: Human, Mouse WB, IHC Host: Mouse Monoclonal 172C1094 unconjugated
anti-Retinoblastoma Protein (Rb Protein) (pSer795) antibodyRb Protein Reactivity: Human, Mouse, Rat WB, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
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Application Notes
- IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C/1 year
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Expiry Date
- 12 months
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- Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
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Background
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Synonyms: RB1, Retinoblastoma-associated protein, p105-Rb, pRb, Rb, pp110
Background: The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008],
Gene Name: RB1
Protein Name: Retinoblastoma-associated protein
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Molecular Weight
- 106 kDa
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Gene ID
- 5925
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OMIM
- 109800
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UniProt
- P06400
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Pathways
- Mitotic G1-G1/S Phases
Target
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