PDE10A antibody (AA 21-70)

Catalog No. ABIN1451106

The Rabbit Polyclonal anti-PDE10A antibody (ABIN1451106) specifically detects PDE10A in WB, ELISA and IHC. The antibody is reactive with Human and Rat samples.

Quick Overview for PDE10A antibody (AA 21-70) (ABIN1451106)

Target: PDE10A (phosphodiesterase 10A (PDE10A))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE10A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PDE10A Antibody

Binding Specificity: AA 21-70

Purpose: PDE10A Antibody

Specificity: PDE10A Polyclonal Antibody detects endogenous levels of PDE10A protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human PDE10A. AA range:21-70

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PDE10A

Target: PDE10A (phosphodiesterase 10A (PDE10A))

Alternative Name: PDE10A

Background:

Synonyms: PDE10A; cAMP and cAMP-inhibited cGMP 3'; 5'-cyclic phosphodiesterase 10A

Background: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2011],

Gene Name: PDE10A

Protein Name: cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

Molecular Weight: 88 kDa

Gene ID: 10846

OMIM: 610652

UniProt: Q9Y233

Pathways: cAMP Metabolic Process