Thrombomodulin antibody (AA 526-575)

Catalog No. ABIN1451724

The Rabbit Polyclonal anti-Thrombomodulin antibody (ABIN1451724) specifically detects Thrombomodulin in WB and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for Thrombomodulin antibody (AA 526-575) (ABIN1451724)

Target: Thrombomodulin (THBD)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Thrombomodulin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Thrombomodulin Antibody

Binding Specificity: AA 526-575

Purpose: CD141 Antibody

Specificity: CD141 Polyclonal Antibody detects endogenous levels of CD141 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human THBD. AA range:526-575

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Thrombomodulin

Target: Thrombomodulin (THBD)

Alternative Name: THBD

Background:

Synonyms: THBD, THRM, Thrombomodulin, TM, Fetomodulin, CD antigen CD141

Background: The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq, Jul 2008],

Gene Name: THBD

Protein Name: Thrombomodulin

Molecular Weight: 60 kDa

Gene ID: 7056

OMIM: 188040

UniProt: P07204