NFE2L3 antibody (AA 491-540)

Catalog No. ABIN1452018

The Rabbit Polyclonal anti-NFE2L3 antibody (ABIN1452018) specifically detects NFE2L3 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for NFE2L3 antibody (AA 491-540) (ABIN1452018)

Target: NFE2L3 (Nuclear Factor (erythroid-Derived 2)-Like 3 (NFE2L3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFE2L3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NFE2L3 Antibody

Binding Specificity: AA 491-540

Purpose: Nrf3 Antibody

Specificity: Nrf3 Polyclonal Antibody detects endogenous levels of Nrf3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human NFE2L3. AA range:491-540

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for NFE2L3

Target: NFE2L3 (Nuclear Factor (erythroid-Derived 2)-Like 3 (NFE2L3))

Alternative Name: NFE2L3

Background:

Synonyms: NFE2L3; NRF3; Nuclear factor erythroid 2-related factor 3; NF-E2-related factor 3; NFE2-related factor 3; Nuclear factor; erythroid derived 2, like 3

Background: This gene encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18. [provided by RefSeq, Mar 2009],

Gene Name: NFE2L3

Protein Name: Nuclear factor erythroid 2-related factor 3

Molecular Weight: 76 kDa

Gene ID: 9603

OMIM: 604135

UniProt: Q9Y4A8