EPH Receptor A2 antibody (AA 131-180)

Catalog No. ABIN1452075

The Rabbit Polyclonal anti-EPH Receptor A2 antibody (ABIN1452075) specifically detects EPH Receptor A2 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for EPH Receptor A2 antibody (AA 131-180) (ABIN1452075)

Target: EPH Receptor A2 (EPHA2)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPH Receptor A2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-EPH Receptor A2 Antibody

Binding Specificity: AA 131-180

Purpose: EphA2 Antibody

Specificity: EphA2 Polyclonal Antibody detects endogenous levels of EphA2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human EPHA2. AA range:131-180

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for EPH Receptor A2

Target: EPH Receptor A2 (EPHA2)

Alternative Name: EPHA2

Background:

Synonyms: EPHA2, ECK, Ephrin type-A receptor 2, Epithelial cell kinase, Tyrosine-protein kinase receptor ECK

Background: This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.[provided by RefSeq, May 2010],

Gene Name: EPHA2

Protein Name: Ephrin type-A receptor 2

Molecular Weight: 108 kDa

Gene ID: 1969

OMIM: 176946

UniProt: P29317

Pathways: RTK Signaling