EPH Receptor B1 antibody (AA 841-890)

Catalog No. ABIN1452081

The Rabbit Polyclonal anti-EPH Receptor B1 antibody (ABIN1452081) specifically detects EPH Receptor B1 in WB and ELISA. The antibody is reactive with Human, Mouse, Rat and Monkey samples.

Quick Overview for EPH Receptor B1 antibody (AA 841-890) (ABIN1452081)

Target: EPH Receptor B1 (EPHB1)

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPH Receptor B1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-EPH Receptor B1 Antibody

Binding Specificity: AA 841-890

Purpose: EphB1 Antibody

Specificity: EphB1 Polyclonal Antibody detects endogenous levels of EphB1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human EPHB1. AA range:841-890

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for EPH Receptor B1

Target: EPH Receptor B1 (EPHB1)

Alternative Name: EPHB1

Background:

Synonyms: EPHB1, ELK, EPHT2, HEK6, NET, Ephrin type-B receptor 1, ELK, EPH tyrosine kinase 2, EPH-like kinase 6, EK6, hEK6, Neuronally-expressed EPH-related tyrosine kinase, NET, Tyrosine-protein kinase receptor EPH-2

Background: Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family.The protein encoded by this gene is a receptor for ephrin-B family members. [provided by RefSeq, Jul 2008],

Gene Name: EPHB1

Protein Name: Ephrin type-B receptor 1

Molecular Weight: 109 kDa

Gene ID: 2047

OMIM: 600600

UniProt: P54762

Pathways: RTK Signaling