PAK7 antibody (AA 661-710)
Quick Overview for PAK7 antibody (AA 661-710) (ABIN1452093)
Target
See all PAK7 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 661-710
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Purpose
- PAK5 Antibody
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Specificity
- PAK5 Polyclonal Antibody detects endogenous levels of PAK5 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- The antiserum was produced against synthesized peptide derived from human PAK7. AA range:661-710
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Isotype
- IgG
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Application Notes
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C/1 year
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Expiry Date
- 12 months
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- PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))
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Alternative Name
- PAK7
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Background
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Synonyms: PAK7, KIAA1264, PAK5, Serine/threonine-protein kinase PAK 7, p21-activated kinase 5, PAK-5, p21-activated kinase 7, PAK-7
Background: The protein encoded byThis gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008],
Gene Name: PAK7
Protein Name: Serine/threonine-protein kinase PAK 7
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Molecular Weight
- 80 kDa
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Gene ID
- 57144
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OMIM
- 608038
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UniProt
- Q9P286
Target
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