MCPH1 antibody (AA 91-140)

Catalog No. ABIN1452183

The Rabbit Polyclonal anti-MCPH1 antibody (ABIN1452183) specifically detects MCPH1 in WB, ELISA, IHC and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for MCPH1 antibody (AA 91-140) (ABIN1452183)

Target: MCPH1 (Microcephalin 1 (MCPH1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCPH1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MCPH1 Antibody

Binding Specificity: AA 91-140

Purpose: Microcephalin Antibody

Specificity: Microcephalin Polyclonal Antibody detects endogenous levels of Microcephalin protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human MCPH1. AA range:91-140

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MCPH1

Target: MCPH1 (Microcephalin 1 (MCPH1))

Alternative Name: MCPH1

Background:

Synonyms: MCPH1, Microcephalin

Background: This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010],

Gene Name: MCPH1

Protein Name: Microcephalin

Molecular Weight: 92 kDa

Gene ID: 79648

OMIM: 251200

UniProt: Q8NEM0

Pathways: Stem Cell Maintenance