Aquaporin 4 antibody (AA 204-253)

Catalog No. ABIN1452942

The Rabbit Polyclonal anti-Aquaporin 4 antibody (ABIN1452942) specifically detects Aquaporin 4 in WB, IHC, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Aquaporin 4 antibody (AA 204-253) (ABIN1452942)

Target: Aquaporin 4 (AQP4)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aquaporin 4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Aquaporin 4 Antibody

Binding Specificity: AA 204-253

Purpose: AQP4 Antibody

Specificity: AQP4 Polyclonal Antibody detects endogenous levels of AQP4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human AQP4. AA range:204-253

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Aquaporin 4

Target: Aquaporin 4 (AQP4)

Alternative Name: AQP4

Background:

Synonyms: AQP4, Aquaporin-4, AQP-4, Mercurial-insensitive water channel, MIWC, WCH4

Background: This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. This protein is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2015],

Gene Name: AQP4

Protein Name: Aquaporin-4

Molecular Weight: 34 kDa

Gene ID: 361

OMIM: 600308

UniProt: P55087

Pathways: Sensory Perception of Sound