PPT1 antibody (AA 16-65)

Catalog No. ABIN1453140

The Rabbit Polyclonal anti-PPT1 antibody (ABIN1453140) specifically detects PPT1 in IHC, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PPT1 antibody (AA 16-65) (ABIN1453140)

Target: PPT1 (Palmitoyl-Protein Thioesterase 1 (PPT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPT1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-PPT1 Antibody

Binding Specificity: AA 16-65

Purpose: CLN1 Antibody

Specificity: CLN1 Polyclonal Antibody detects endogenous levels of CLN1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human CLN1. AA range:16-65

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PPT1

Target: PPT1 (Palmitoyl-Protein Thioesterase 1 (PPT1))

Alternative Name: CLN1

Background:

Synonyms: PPT1, PPT, Palmitoyl-protein thioesterase 1, PPT-1, Palmitoyl-protein hydrolase 1

Background: The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2008],

Gene Name: PPT1

Protein Name: Palmitoyl-protein thioesterase 1

Molecular Weight: 34 kDa

Gene ID: 5538

OMIM: 600722

UniProt: P50897

Pathways: SARS-CoV-2 Protein Interactome