OXT antibody (AA 40-89)

Catalog No. ABIN1453629

The Rabbit Polyclonal anti-OXT antibody (ABIN1453629) specifically detects OXT in WB, ELISA, IHC and IF. The antibody is reactive with Human and Rat samples.

Quick Overview for OXT antibody (AA 40-89) (ABIN1453629)

Target: OXT (Oxytocin, Prepropeptide (OXT))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OXT antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-OXT Antibody

Binding Specificity: AA 40-89

Purpose: Neurophysin I Antibody

Specificity: Neurophysin I Polyclonal Antibody detects endogenous levels of Neurophysin I protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human Neurophysin I. AA range:40-89

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for OXT

Target: OXT (Oxytocin, Prepropeptide (OXT))

Alternative Name: Neurophysin I

Background:

Synonyms: OXT, OT, Oxytocin-neurophysin 1, OT-NPI

Background: This gene encodes a precursor protein that is processed to produce oxytocin and neurophysin I. Oxytocin is a posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. [provided by RefSeq, Dec 2013],

Gene Name: OXT

Protein Name: Oxytocin-neurophysin 1

Molecular Weight: 12 kDa

Gene ID: 5020

OMIM: 167050

UniProt: P01178

Pathways: Myometrial Relaxation and Contraction, Feeding Behaviour