NEFM antibody (AA 542-591)

Catalog No. ABIN1453647

The Rabbit Polyclonal anti-NEFM antibody (ABIN1453647) specifically detects NEFM in WB, IHC and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for NEFM antibody (AA 542-591) (ABIN1453647)

Target: NEFM (Neurofilament Triplet M Protein (NEFM))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEFM antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-NEFM Antibody

Binding Specificity: AA 542-591

Purpose: NF-M Antibody

Specificity: NF-M Polyclonal Antibody detects endogenous levels of NF-M protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human NF-M. AA range:542-591

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for NEFM

Target: NEFM (Neurofilament Triplet M Protein (NEFM))

Alternative Name: NF-M

Background:

Synonyms: NEFM, NEF3, NFM, Neurofilament medium polypeptide, NF-M, 160 kDa neurofilament protein, Neurofilament 3, Neurofilament triplet M protein

Background: neurofilament, medium polypeptide(NEFM) Homo sapiens Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites.This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008],

Gene Name: NEFM

Protein Name: Neurofilament medium polypeptide

Molecular Weight: 102 kDa

Gene ID: 4741

OMIM: 162250

UniProt: P07197

Pathways: Brown Fat Cell Differentiation